"Shiho, won't you regret what you are about to do? If so, I'm totally on your side! Well, it will be you nineteenth birthday next time. Bye-bye, honey. Oh yes, maybe it's about time I told you... The truth is, your mom is making a truly terrifying drug at the moment. My lab mates are getting really excited about it, they say it's like a dream drug. Your dad and I are putting all our hopes on it and calling it the Silver Bullet! But in order to complete the drug, your dad and I will have to leave you and your sister. Please understand, Shiho."
— Part of Elena's message on Shiho's 18th tape.
