There are genetic abnormalities that occur in mitochondrial DNA and they also affect an individual. Mitochondrial DNA is inherited from the mother, for at the time of fertilization of an egg the mitochondrion of the sperm does not enter the egg. The egg contains mother's mitochondria and as such the child only possesses mother's mitochondria. Due to such mode of inheritance, the genetic abnormality will be expressed in all children of the abnormality-carrying mother and in no children of the father with the same abnormality.
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