Week 3

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Part 2 : The blood system

Function of blood

*Nutrition 

Blood carries nutritive substances from the gut to the tissues


*Respiration 

Pick up O2 from lung to tissues 

Carries CO2 from tissues to lung


*Excretion

Transport metabolic waste products to kidney for disposal 


 *Transport

Carries various substance into the target tissues


*Protection

White blood cells serve as a defense mechanisms of the body


*Homeostasis

Regulate body temp and pH of body fluids


*Clotting mechanism 

To stop loss of blood 

Repair the damaged of blood vessel 


Formation of blood cells

Process of the blood cells formation----Hae-mato-poiesis

[Occurs in red bone marrow]


Ery-thro-poiesis  [Formation of  red blood cells]

Leu-co-poiesis [Formation of white blood cells]

Throm-bo-poiesis [Formation of platelets]


Blood Cell Anatomy and Function 

* Leu-ko-cytes [White blood cell]

1. Granulo-cytes  [Contain granules in their cytoplasm]

    a. Eosinophils  [ Bi-lobed nucleus]

       - Kill parasites

        -Break down histamine in allergic reaction

  b. Neutro-phil  [ Multi-lobed nucleus]

       -Consume foreign particles/ bacteria and digest them

  c. Baso-phils  [Irregular nucleus]

     - Release anticoagulant and histamine


2.  A-granulo-cytes [Not contain granules in cytoplasm]

       a.  Mono-cytes [ Large single nucleus]

        - Largest leucocytes

        -Important function in immunity 

        - Consume large particles 


      b. Lympho-cytes [Large round, single almost filled the cell nucleus]

         -Play important role in immunity


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Disorders of blood 

1. Leukemia [Abnormal production of white blood cells]

-Excess production of WBCs interferes with normal RBCs and platelets formation----[anemia and excessive bleeding from minor injury]

Symptoms 

-Easy bleeding / bruising

-Frequent infection   


2. Anemia  [decrease in the no. RBCs or hemoglobin]

-Lower ability for the blood to carry oxygen to body tissues 

Symptoms 

-Lack of energy 

-Shortness of breath 

-pale skin 

-Fatigue



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