Lilac is the first one to activate the werewolf curse when she turned 17 and got her drivers license. She ended up in a car crash that killed her best friend. Shortly after her sister Elenor activates her curse by getting drunk at a party and carrying a knife... you can see where that leads, it does get them closer so that's a plus. Elenor is 17 and Lilac is 19.
Mikeal and Marshall are still 5 so they haven't activated the werewolf curse yet and you hope they never do. (Yes they occasionally fall out of their beds.)
Lucas activated his curse when he was 20 after his girlfriend broke up with him. He was mad and upset and had a few drinks and then started a fight... he won.
Ethan still hasn't activated his curse and he hopes he never will but this makes him extremely cautious, shy, closed off and anxious. You hope one day he will outgrow this and realise that he can still live a good life. He is 15.