BIOMED
Pathophysiology
Everything be alphabetical here (except for Homeostasis at the bottom) 😘
(& Mental Health, Lmao)
There are a lot of neonatal conditions covered, seen in high level NICU/NCCU Units.
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Table of Contents:
1 | Ageing
2 | Canc...
Diabetes Mellitus (DM) is not one, but a variety of chronic disorders affecting people across the lifespan, characterised very generally by either an insulin resistance/deficiency or levels of glucagon. Essentially, this is a disease wherein insulin fails to maintain homeostatic balance. Of course this is a very broad topic overview, however this chapter will delve into the endocrine relevance, what the metabolic process looks like when working normally, versus when we encounter a person either borderline, or with a diagnosis of DM.
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Glucose Homeostasis & DM
In order to achieve cellular respiration (wherein glucose in converted into ATP), the process begins with the consumption of food. I'm not going to go into great detail about these kinds of sugars as of yet, but the sexy Venn diagram above is a good demonstrative starting point for this area of study (yes, we all love a good diagram).
As you may have heard, BGL's (or BSL's) are what we refer to the blood glucose/sugar level, and is what we are referring to when we refer to glucose in circulation. Of course, in greatly high or low (hypo/hyperglycaemia), we may detect a change in plasma osmolarity, and therefore blood pressure, as this is a component in the blood. However for the purpose of this chapter, I'll leave that for another day.
All we must really understand by this point, is that we consume food, which is broken down (in the jejumum if you're curious/your course requires you to know that like mine does), and the breakdown is necessary for the eventual creation of ATP which fuels obviously all functions in the human body.;
A little more detail:
Hexose monosaccharide: a simple sugar with 6 carbon atoms
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This sugar will eventually be broken down into 2x 3 carbon molecules
