"Charley horse" is another name for a muscle spasm. Charley horses can occur in virtually any muscle, but they are most common in the legs. These spasms are marked by extremely uncomfortable muscle contractions. The muscles don't relax for several seconds or more, and the pain can be quite severe.
A number of factors may cause a muscle frank or spasm. The most common causes of Charley horses include: inadequate blood flow to the muscle, muscle injuries, exercising in excessive heat or cold, overuse of a specific muscle, stress, not stretching before exercise, nerve compression in the spine, taking diuretics which can lead to low potassium, mineral depletion, and dehydration.
Source: {http://www.healthline.com/health/Charley-horse%23overview1}
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