Sheldon, Amy, Howard and Leonard

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Amy: Your neurology department loaned me a culture of prions for my research on bovine spongiform encephalopathy.

Sheldon: She popped by to borrow a cup of mad cow disease.

Amy: It's hard to make degenerative brain maladies hilarious, and yet somehow you do it.

Howard: That's fun to have in a lunchroom.

Amy: The real fun starts when you get to pick the rat you're going to feed it to, and maybe you choose the beady-eyed little mother who's been biting you all week.

Howard: Please, we're eating. Can we get that off the table and change the subject?

Sheldon: Can we? Stand back while I turn this conversation into a conver-sensation.

Leonard: This time, it's your fault.

Sheldon: I have 100 alphabetized topics from artichoke, come on, people, it's just a giant thistle, to zzz, the onamona-poetry of sleep.

Leonard: Amy, how long would it take for that mad cow disease to kill me?

Amy: I don't know, four or five years.

Leonard: No, it's not gonna do it.

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