A/N: so out of all the shows, that were brought up. Next She-Hulk, Ms Marvel, Loki and even WandaVision. The show that has my attention a lot would be Marvel's What If. Which will be an animated series.
So next to the series going to be written by Ashley Bradley (who did Trollhunters) while the directing will be done by Bryan Andrews (who's been the storyboard artist for Samurai Jack, movies and other MCU films).
However, What has my curiosity on this is with the animation. Now, this is mostly a best guess and they'll likely only be using one Animation studio for this series. But, What if this series was done where each one if Scenario in each episode is done by a different Animation studio each time.
One could have the art and animation to the marvel shows that played on Disney XD, another could have more simpler art and animation and other could have like an anime-ish art and animation style.
For the moment, it might seem like it might not be the case. But, think about it. It could make an interesting take that they could try to pull for this what if series.