A/N: So I've seen multiple stuff going around that Sony eventually wants to do a film a film based on the Sinister Six. My Only Question is on how would that work exactly.
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I mean, this isn't like Suicide Squad where you have rouges who are used as disposable assets in high-risk missions for the United States government. The Sinister Six are a Six Man Group of Villains that was formed to Kill Spider-Man.
Maybe they could do something with the 6 in a later Spider-Man film (Depending on Director and Team) but as a Solo film, I don't think they could work.