ADDISON VS CUSHING

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#MSSeries
Endocrine
    -series of glands that produce and secrete hormones

*Addison and Cushing disease/disorder are each other’s opposites. Pareho silang problema sa Endocrine na kung saan ay pareho silang involved sa adrenal glands. Ang adrenal glands ay may responsibilidad sa paggawa ng cortisol at aldosterone. Ang cortisol at aldosterone most important hormones sa katawan. Kaya excesses or deficiencies of nito ay nagreresulta sa problem sa katawan o clinical problems such as Addison and Cushing.

Addison's disease
   -low levels of cortisol and aldosterone
   -caused by an autoimmune disease that damages the adrenal gland
  ✴S/Sx:
        ~bronze skin
        ~changes in distribution of body hair
        ~GI disturbances
        ~hypocalcemia
        ~postural hypotension
        ~weight loss
        ~hypercalcemia
        ~hypoglycemia
        ~hyponatremia
    >Adrenal crisis:
      •profound fatigue
      •dehydration
      •vasular collapse
      •renal shut down
      •⬇ serum Na
      •⬆ serum K
      •wt. loss
   ✴txt: lifelong replacement therapy (corticosteroids or a mineralocorticoid)
   ✴nrsg mgt: ABC (may cause hypotension)
                            IVF
                            monitor blood glucose (hypoglycemia)

Cushing's disease
     -excessive levels of cortisol
  ✴S/Sx:
        ~emotional instability
        ~moon face
        ~buffalo hump
        ~osteoporosis
        ~trancal obesity
        ~thinning of scalp hair
        ~acne
        ~increase facial hair
        ~cardiac hypertrophy and hypertension
        ~hyperplasia (adrenal)
        ~tumor (adrenal)
        ~striae of the skin (stretchmark)
        ~easy bruising
        ~hypocalcemia
        ~hyperglycemia
        ~hypokalemia
        ~hypernatremia
       ~weight gain
   ✴txt: steroids (🚫 or ⬇ dosage)
   ✴nrsg mgt: ABC (mental and hypertension)
                           DAILY weight
                           IVF
                           monitor blood glucose
                           monitor for DVT
                           prevent infection
                           Diet: high CHO/calories, Na and CHON, low K

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