Persona is a long running game series with different protagonists and stories. So the best way to know which of them is the best is by pitting the Protagonists of Persona 3, 4 and 5 against each other
Minato Aristato
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Superhuman Physical Characteristics
Summoning
Fire Manipulation
Ice Manipulation
Light Manipulation
Healing
Darkness Manipulation
Air Manipulation
Electricity Manipulation
Energy Manipulation
Emotion Manipulation
Regeneration
Almighty skills that bypass magical defenses and resistances.
High Resistanceto Elemental Manipulation, Light Manipulation, Darkness Manipulation.
Resistance Negation and Power Nullification.
Resistant to Death Manipulation .
Sealing with Great Seal
Status Effect Inducement and Statistics Amplification.
Can One Hit Kill with Hama/Mudo skills.
Weapons
Evoker
Sword
Notable Attacks/Techniques:
The Great Seal
Uses his Soul to seal his opponent away. He can survive without it for a least a month.
Persona
A manifestation of one's psyche in the form of a powerful guardian spirit. They are typically summoned via the usage of an Evoker (a gun-shaped prop) that is meant to emulate the lethal circumstances when Personae usually manifest. As he possesses the Wild Card, he has over 180 personae as opposed to the most users having 1. Skills his Personae can use include:
Nilfheim:
Creates a frosty explosion that completely freezes one target.
Samsara:
Uses the power of Holy/Light to slay his enemies with a massive light burst. Has an 80% chance of inflicting instant death.
Pralaya:
Creates a massive energy explosion that pierces all enemies. Has a chance to make them stricken with fear.