Jane Rizzoli is a detective that doesn't play around on homicides. When she comes across one that is drug related, it pulls at her heart. She has seen what drugs can do to a family. She has gone through this herself with her own family because of her baby brother, Tommy.
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This story follows Boston Homicide Detective Jane Rizzoli as she races to find her wife, Chief Medical Examiner Dr. Maura Isles after she has been abducted.